Random mutations much more easily debilitate genes than improve them, and that this is true even of the helpful mutations. Let me emphasize, our experience with malaria’s effects on humans (arguably our most highly studied genetic system) shows that most helpful mutations degrade genes. What’s more, as a group the mutations are incoherent, meaning that they are not adding up to some new system. They are just small changes - mostly degradative - in pre-existing, unrelated genes. The take-home lesson is that this is certainly not the kind of process we would expect to build the astonishingly elegant machinery of the cell. If random mutation plus selective pressure substantially trashes the human genome, why should we think that it would be a constructive force in the long term? There is no reason to think so.
Michael J. BeheTags: science biology chance evolution darwinism macro-evolution macroevolution malaria mutations
She wasted and grew so thin that she no longer was a little girl, but the shadow of a little girl. The flame of her life flickered so faintly that it appeared sufficient to blow at it to extinguish it. Stas understood that death did not have to wait for a third attack to take her and he expected it any day or any hour.
Henryk SienkiewiczTags: africa death death-and-dying sickness wilderness disease malaria
He knows that there will be days ahead, long, tedious days which have no real beginning or ending, but which run together into night and out of it without changing color, or sound, or meaning. He will lie in his bed feeling the minutes and the hours pass through his body like an endless ribbon of pain because time becomes pain then. Light and darkness become pain; all his senses exist only to receive it, to transmit to his mind again and again, with ceaseless repetition, the simple fact that now he is dying.
Beryl MarkhamTags: death blackwater malaria
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