My laboratory is interested in the related challenges of understanding the origin of life on the early earth, and constructing synthetic cellular life in the laboratory. Focusing on artificial life frees us to explore novel chemical systems, but what we learn from these systems helps us to understand possible pathways leading to the origin of life. Our basic design for a synthetic cell involves the encapsulation of a spontaneously replicating nucleic acid, which acts as the genetic material, within a spontaneously replicating membrane vesicle, which provides spatial localization. We are using chemical synthesis to make nucleic acids with modified nucleobases and sugar-phosphate backbones.

Jack W. Szostak

Tag: science biology chemistry nobel-laureate origin-of-life artificial-life early-earth early-life first-life laboratory synthetic-life



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Time... is an essential requirement for effective research. An investigator may be given a palace to live in, a perfect laboratory to work in, he may be surrounded by all the conveniences money can provide; but if his time is taken from him he will remain sterile.

Walter Bradford Cannon

Tag: science money progress time investigation research sterile laboratory



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Much as I admired the elegance of physical theories, which at that time geology wholly lacked, I preferred a life in the woods to one in the laboratory.

J. Tuzo Wilson

Tag: science life theories nature wonder admiration elegance geology woods scientist plate-tectonics scenery scientific-theories laboratory lab



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